Exome Sequence Analysis of 14 Families With High Myopia

PURPOSE: To identify causal gene mutations in 14 families with autosomal dominant (AD) high myopia using exome sequencing. METHODS: Select individuals from 14 large Caucasian families with high myopia were exome sequenced. Gene variants were filtered to identify potential pathogenic changes. Sanger...

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Detalles Bibliográficos
Autores principales: Kloss, Bethany A., Tompson, Stuart W., Whisenhunt, Kristina N., Quow, Krystina L., Huang, Samuel J., Pavelec, Derek M., Rosenberg, Thomas, Young, Terri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382835/
https://www.ncbi.nlm.nih.gov/pubmed/28384719
http://dx.doi.org/10.1167/iovs.16-20883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382835/
https://www.ncbi.nlm.nih.gov/pubmed/28384719
http://dx.doi.org/10.1167/iovs.16-20883

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