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A specific fluorescent probe reveals compromised activity of methionine sulfoxide reductases in Parkinson's disease
Oxidation of methionine residues to methionine sulfoxide (MetSO) may cause changes in protein structure and function, and may eventually lead to cell damage. Methionine sulfoxide reductases (Msrs) are the only known enzymes that catalyze the reduction of MetSO back to methionine by taking reducing e...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382841/ https://www.ncbi.nlm.nih.gov/pubmed/28451363 http://dx.doi.org/10.1039/c6sc04708d |