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Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy

Alzheimer’s disease is characterized by the combined presence of amyloid plaques and tau pathology, the latter being correlated with the progression of clinical symptoms. Neuroinflammatory changes are thought to be major contributors to Alzheimer’s disease pathophysiology, even if their precise role...

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Detalles Bibliográficos
Autores principales: Laurent, Cyril, Dorothée, Guillaume, Hunot, Stéphane, Martin, Elodie, Monnet, Yann, Duchamp, Marie, Dong, Yuan, Légeron, François-Pierre, Leboucher, Antoine, Burnouf, Sylvie, Faivre, Emilie, Carvalho, Kévin, Caillierez, Raphaëlle, Zommer, Nadège, Demeyer, Dominique, Jouy, Nathalie, Sazdovitch, Veronique, Schraen-Maschke, Susanna, Delarasse, Cécile, Buée, Luc, Blum, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382942/
https://www.ncbi.nlm.nih.gov/pubmed/27818384
http://dx.doi.org/10.1093/brain/aww270