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A tetraethylene glycol coat gives gold nanoparticles long in vivo half-lives with minimal increase in size

In this study, we describe the experiments determining whether coating gold nanoparticles with tetraethylene glycol (TEG) provides pharmacologically relevant advantages, such as increased serum half-life and resistance to protein adsorption. Monodisperse TEG-coated, NaBH(4)-reduced gold nanoparticle...

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Detalles Bibliográficos
Autores principales: Willett, Julian DS, Lawrence, Marlon G, Wilder, Jennifer C, Smithies, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383068/
https://www.ncbi.nlm.nih.gov/pubmed/28408825
http://dx.doi.org/10.2147/IJN.S121486