Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats

The purpose of the research was to explore the therapeutic action of simvastatin-loaded poly(ethylene glycol)-b-poly(gamma-benzyl l-glutamate) (PEG-b-PBLG(50)) on intestinal ischemia/reperfusion injury (II/RI) through downregulating bone morphogenetic protein 4 (BMP4)/cyclooxygenase-2 (COX-2) pathwa...

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Detalles Bibliográficos
Autores principales: Tong, Fei, Dong, Bo, Chai, Rongkui, Tong, Ke, Wang, Yini, Chen, Shipiao, Zhou, Xinmei, Liu, Daojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383092/
https://www.ncbi.nlm.nih.gov/pubmed/28408819
http://dx.doi.org/10.2147/IJN.S126063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383092/
https://www.ncbi.nlm.nih.gov/pubmed/28408819
http://dx.doi.org/10.2147/IJN.S126063

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