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Increased expression of prion protein gene is accompanied by demethylation of CpG sites in a mouse embryonal carcinoma cell line, P19C6

Elucidation of the processes regulating the prion protein gene (Prnp) is an important key to understanding the development of prion disorders. In this study, we explored the involvement of DNA methylation in Prnp transcriptional regulation during neuronal differentiation of embryonic carcinoma P19C6...

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Detalles Bibliográficos
Autores principales: DALAI, Wuyun, MATSUO, Eiko, TAKEYAMA, Natsumi, KAWANO, Junichi, SAEKI, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383191/
https://www.ncbi.nlm.nih.gov/pubmed/28132962
http://dx.doi.org/10.1292/jvms.16-0554