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Doxycycline protects against ROS-induced mitochondrial fragmentation and ISO-induced heart failure
In addition to their anti-bacterial action, tetracyclines also have complex biological effects, including the modification of mitochondrial protein synthesis, metabolism and gene-expression. Long-term clinical studies have been performed using tetracyclines, without significant side effects. Previou...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383248/ https://www.ncbi.nlm.nih.gov/pubmed/28384228 http://dx.doi.org/10.1371/journal.pone.0175195 |