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KChIP2 regulates the cardiac Ca(2+) transient and myocyte contractility by targeting ryanodine receptor activity

Pathologic electrical remodeling and attenuated cardiac contractility are featured characteristics of heart failure. Coinciding with these remodeling events is a loss of the K(+) channel interacting protein, KChIP2. While, KChIP2 enhances the expression and stability of the Kv4 family of potassium c...

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Detalles Bibliográficos
Autores principales: Nassal, Drew M., Wan, Xiaoping, Liu, Haiyan, Laurita, Kenneth R., Deschênes, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383259/
https://www.ncbi.nlm.nih.gov/pubmed/28384221
http://dx.doi.org/10.1371/journal.pone.0175221