DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target

Dengue is the most common mosquito-borne viral disease in humans. Changes of lipid-related metabolites in endoplasmic reticulum of dengue virus (DENV) infected cells have been associated with replicative complexes formation. Previously, we reported that DENV infection inhibits HMGCR phosphorylation...

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Detalles Bibliográficos
Autores principales: Soto-Acosta, Rubén, Bautista-Carbajal, Patricia, Cervantes-Salazar, Margot, Angel-Ambrocio, Antonio H., del Angel, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383345/
https://www.ncbi.nlm.nih.gov/pubmed/28384260
http://dx.doi.org/10.1371/journal.ppat.1006257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383345/
https://www.ncbi.nlm.nih.gov/pubmed/28384260
http://dx.doi.org/10.1371/journal.ppat.1006257

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