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Immune response of rats vaccinated orally with various plant-expressed recombinant cysteine proteinase constructs when challenged with Fasciola hepatica metacercariae

BACKGROUND: Cysteine proteinases of Fasciola hepatica are important candidates for vaccine antigens because of their role in fluke biology and host-parasite relationships. In our previous experiments, we found that a recombinant cysteine proteinase cloned from adult F. hepatica (CPFhW) can protect r...

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Detalles Bibliográficos
Autores principales: Kesik-Brodacka, Malgorzata, Lipiec, Agnieszka, Kozak Ljunggren, Monika, Jedlina, Luiza, Miedzinska, Katarzyna, Mikolajczak, Magdalena, Plucienniczak, Andrzej, Legocki, Andrzej B., Wedrychowicz, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383346/
https://www.ncbi.nlm.nih.gov/pubmed/28333957
http://dx.doi.org/10.1371/journal.pntd.0005451