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Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells

2,5-hexanedione (HD) is the ultimate neurotoxic metabolite of hexane, causing the progression of nerve diseases in human. It was reported that HD induced apoptosis and oxidative stress. Taurine has been shown to be a potent antioxidant. In the present study, we investigated the protection of taurine...

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Detalles Bibliográficos
Autores principales: LI, Shuangyue, GUAN, Huai, QIAN, Zhiqiang, SUN, Yijie, GAO, Chenxue, LI, Guixin, YANG, Yi, PIAO, Fengyuan, HU, Shuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Occupational Safety and Health, Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383408/
https://www.ncbi.nlm.nih.gov/pubmed/27840369
http://dx.doi.org/10.2486/indhealth.2016-0044