Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3

The growth factor and cytokine regulated transcription factor STAT3 is required for the self-renewal of several stem cell types including tumor stem cells from glioblastoma. Here we show that STAT3 inhibition leads to the upregulation of the histone H3K27me2/3 demethylase Jmjd3 (KDM6B), which can re...

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Detalles Bibliográficos
Autores principales: Sherry-Lynes, Maureen M., Sengupta, Sejuti, Kulkarni, Shreya, Cochran, Brent H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383422/
https://www.ncbi.nlm.nih.gov/pubmed/28384648
http://dx.doi.org/10.1371/journal.pone.0174775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383422/
https://www.ncbi.nlm.nih.gov/pubmed/28384648
http://dx.doi.org/10.1371/journal.pone.0174775

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