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Myeloid progenitor cluster formation drives emergency and leukemic myelopoiesis

While many aspects of blood production are now well understood, the spatial organization of myeloid differentiation in the bone marrow (BM) remains unknown. Here, we use imaging to track granulocyte/macrophage progenitor (GMP) behavior during emergency and leukemic myelopoiesis. At steady state, we...

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Detalles Bibliográficos
Autores principales: Hérault, Aurélie, Binnewies, Mikhail, Leong, Stephanie, Calero-Nieto, Fernando J., Zhang, Si Yi, Kang, Yoon-A, Wang, Xiaonan, Pietras, Eric M., Chu, S. Haihua, Barry-Holson, Keegan, Armstrong, Scott, Göttgens, Berthold, Passegué, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383507/
https://www.ncbi.nlm.nih.gov/pubmed/28355185
http://dx.doi.org/10.1038/nature21693