Broad TCR Repertoire And Diverse Structural Solutions To Recognition Of An Immunodominant CD8 T Cell Epitope

A keystone of antiviral immunity is CD8 T-cell recognition of viral peptides bound to MHC-I proteins. The recognition mode of individual T cell receptors (TCRs) has been studied in some detail, but how TCR variation functions in providing a robust response to viral antigen is unclear. The influenza...

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Detalles Bibliográficos
Autores principales: Song, InYoung, Gil, Anna, Mishra, Rabinarayan, Ghersi, Dario, Selin, Liisa K., Stern, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383516/
https://www.ncbi.nlm.nih.gov/pubmed/28250417
http://dx.doi.org/10.1038/nsmb.3383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383516/
https://www.ncbi.nlm.nih.gov/pubmed/28250417
http://dx.doi.org/10.1038/nsmb.3383

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