HIV-Tat protein and amyloid β peptide form multifibrillar structures that cause neurotoxicity

We investigated direct interactions between the human immunodeficiency virus (HIV)-trans-activator of transcription (Tat) protein and amyloid β peptide. Amyloid β-Tat complexes are readily formed extracellularly in the brain. In vitro studies showed that in the presence of Tat, the uniform amyloid f...

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Detalles Bibliográficos
Autores principales: Hategan, Alina, Bianchet, Mario A., Steiner, Joseph, Karnaukhova, Elena, Masliah, Eliezer, Fields, Adam, Lee, Myoung-Hwa, Dickens, Alex M., Haughey, Norman, Dimitriadis, Emilios K., Nath, Avindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383535/
https://www.ncbi.nlm.nih.gov/pubmed/28218748
http://dx.doi.org/10.1038/nsmb.3379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383535/
https://www.ncbi.nlm.nih.gov/pubmed/28218748
http://dx.doi.org/10.1038/nsmb.3379

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