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Enhanced differentiation of mesenchymal stromal cells by three-dimensional culture and azacitidine

BACKGROUND: Mesenchymal stromal cells (MSCs) are useful for cell therapy because of their potential for multilineage differentiation. However, MSCs that are expanded in traditional two-dimensional (2D) culture systems eventually lose their differentiation abilities. Therefore, we investigated whethe...

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Detalles Bibliográficos
Autores principales: Bae, Yoo-Jin, Kwon, Yong-Rim, Kim, Hye Joung, Lee, Seok, Kim, Yoo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383582/
https://www.ncbi.nlm.nih.gov/pubmed/28401097
http://dx.doi.org/10.5045/br.2017.52.1.18