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Generation of hematopoietic stem cells from human embryonic stem cells using a defined, stepwise, serum-free, and serum replacement-free monolayer culture method

BACKGROUND: Embryonic stem cells (ESCs) can be expanded infinitely in vitro and have the potential to differentiate into hematopoietic stem cells (HSCs); thus, they are considered a useful source of cells for HSC production. Although several technical in vitro methods for engineering HSCs from pluri...

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Detalles Bibliográficos
Autores principales: Kim, So-Jung, Jung, Ji-Won, Ha, Hye-Yeong, Koo, Soo Kyung, Kim, Eung-Gook, Kim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383586/
https://www.ncbi.nlm.nih.gov/pubmed/28401100
http://dx.doi.org/10.5045/br.2017.52.1.37