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Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function

The chloride (Cl(-)) channel cystic fibrosis transmembrane conductance regulator (CFTR) is defective in cystic fibrosis (CF), and mutation of its encoding gene leads to various defects such as retention of the misfolded protein in the endoplasmic reticulum, reduced stability at the plasma membrane,...

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Detalles Bibliográficos
Autores principales: Billet, Arnaud, Froux, Lionel, Hanrahan, John W., Becq, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383655/
https://www.ncbi.nlm.nih.gov/pubmed/28439239
http://dx.doi.org/10.3389/fphar.2017.00195