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Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1

BACKGROUND: The transcription factor Ets1 is highly expressed in B lymphocytes. Loss of Ets1 leads to premature B cell differentiation into antibody-secreting cells (ASCs), secretion of autoantibodies, and development of autoimmune disease. Despite the importance of Ets1 in B cell biology, few Ets1...

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Detalles Bibliográficos
Autores principales: Saelee, Prontip, Kearly, Alyssa, Nutt, Stephen L., Garrett-Sinha, Lee Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383717/
https://www.ncbi.nlm.nih.gov/pubmed/28439269
http://dx.doi.org/10.3389/fimmu.2017.00383