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Nifedipine Inhibition of High-Voltage Activated Calcium Channel Currents in Cerebral Artery Myocytes Is Influenced by Extracellular Divalent Cations

Voltage-dependent calcium channels (VDCCs) play an essential role in regulating cerebral artery diameter and it is widely appreciated that the L-type VDCC, Ca(V)1.2, encoded by the CACNA1C gene, is a principal Ca(2+) entry pathway in vascular myocytes. However, electrophysiological studies using 10...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Koide, Masayo, Wellman, George C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383720/
https://www.ncbi.nlm.nih.gov/pubmed/28439241
http://dx.doi.org/10.3389/fphys.2017.00210