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Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics

Recent advances in mass spectrometry (MS)-based proteomics now allow very deep coverage of cellular proteomes. To achieve near-comprehensive identification and quantification, the combination of a first HPLC-based peptide fractionation orthogonal to the on-line LC-MS/MS step has proven to be particu...

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Detalles Bibliográficos
Autores principales: Kulak, Nils A., Geyer, Philipp E., Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383787/
https://www.ncbi.nlm.nih.gov/pubmed/28126900
http://dx.doi.org/10.1074/mcp.O116.065136