Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: synthesis, biological evaluation and molecular docking

BACKGROUND: Various thiourea derivatives have been used as starting materials for compounds with better biological activities. Molecular modeling tools are used to explore their mechanism of action. RESULTS: A new series of thioureas were synthesized. Fluorinated pyridine derivative 4a showed the hi...

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Detalles Bibliográficos
Autores principales: Ghorab, Mostafa M., Alsaid, Mansour S., El-Gaby, Mohamed S. A., Elaasser, Mahmoud M., Nissan, Yassin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383913/
https://www.ncbi.nlm.nih.gov/pubmed/29086809
http://dx.doi.org/10.1186/s13065-017-0258-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383913/
https://www.ncbi.nlm.nih.gov/pubmed/29086809
http://dx.doi.org/10.1186/s13065-017-0258-4

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