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Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

The proneural transcription factor Ascl1 coordinates gene expression in both proliferating and differentiating progenitors along the neuronal lineage. Here, we used a cellular model of neurogenesis to investigate how Ascl1 interacts with the chromatin landscape to regulate gene expression when promo...

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Detalles Bibliográficos
Autores principales: Raposo, Alexandre A.S.F., Vasconcelos, Francisca F., Drechsel, Daniela, Marie, Corentine, Johnston, Caroline, Dolle, Dirk, Bithell, Angela, Gillotin, Sébastien, van den Berg, Debbie L.C., Ettwiller, Laurence, Flicek, Paul, Crawford, Gregory E., Parras, Carlos M., Berninger, Benedikt, Buckley, Noel J., Guillemot, François, Castro, Diogo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383937/
https://www.ncbi.nlm.nih.gov/pubmed/25753420
http://dx.doi.org/10.1016/j.celrep.2015.02.025