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Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis
The proneural transcription factor Ascl1 coordinates gene expression in both proliferating and differentiating progenitors along the neuronal lineage. Here, we used a cellular model of neurogenesis to investigate how Ascl1 interacts with the chromatin landscape to regulate gene expression when promo...
Autores principales: | Raposo, Alexandre A.S.F., Vasconcelos, Francisca F., Drechsel, Daniela, Marie, Corentine, Johnston, Caroline, Dolle, Dirk, Bithell, Angela, Gillotin, Sébastien, van den Berg, Debbie L.C., Ettwiller, Laurence, Flicek, Paul, Crawford, Gregory E., Parras, Carlos M., Berninger, Benedikt, Buckley, Noel J., Guillemot, François, Castro, Diogo S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383937/ https://www.ncbi.nlm.nih.gov/pubmed/25753420 http://dx.doi.org/10.1016/j.celrep.2015.02.025 |
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