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Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report

BACKGROUND: The translocation t(1;19)(q23;p13), which results in the TCF3-PBX1 chimeric gene, is one of the most frequent rearrangements observed in B cell acute lymphoblastic leukemia. It appears in both adult and pediatric patients with B cell acute lymphoblastic leukemia at an overall frequency o...

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Detalles Bibliográficos
Autores principales: Wafa, Abdulsamad, As’sad, Manar, Liehr, Thomas, Aljapawe, Abdulmunim, Al Achkar, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383952/
https://www.ncbi.nlm.nih.gov/pubmed/28385156
http://dx.doi.org/10.1186/s13256-017-1251-1