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Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) and cancer stem cells (CSC) contribute to tumour progression and metastasis. Assessment of transcription factors involved in these two mechanisms can help to identify new targets for an oncological therapy. In this study, we focused on the evalu...

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Detalles Bibliográficos
Autores principales: Lerbs, Tristan, Bisht, Savita, Schölch, Sebastian, Pecqueux, Mathieu, Kristiansen, Glen, Schneider, Martin, Hofmann, Bianca T., Welsch, Thilo, Reissfelder, Christoph, Rahbari, Nuh N., Fritzmann, Johannes, Brossart, Peter, Weitz, Jürgen, Feldmann, Georg, Kahlert, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383957/
https://www.ncbi.nlm.nih.gov/pubmed/28388884
http://dx.doi.org/10.1186/s12885-017-3225-5