Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma

BACKGROUND: Juglone is a natural pigment, which has cytotoxic effect against various human tumor cells. However, its cytotoxicity to glioma cells, especially to tumor stem-like cells (TSCs) has not been demonstrated. METHODS: TSCs of glioma were enriched from U87 and two primary cells (SHG62, and SH...

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Detalles Bibliográficos
Autores principales: Wu, Jinfeng, Zhang, Haibo, Xu, Yang, Zhang, Jingwen, Zhu, Wei, Zhang, Yi, Chen, Liang, Hua, Wei, Mao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383964/
https://www.ncbi.nlm.nih.gov/pubmed/28388894
http://dx.doi.org/10.1186/s12883-017-0843-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383964/
https://www.ncbi.nlm.nih.gov/pubmed/28388894
http://dx.doi.org/10.1186/s12883-017-0843-0

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