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Transcriptomic buffering of cryptic genetic variation contributes to meningococcal virulence

BACKGROUND: Commensal bacteria like Neisseria meningitidis sometimes cause serious disease. However, genomic comparison of hyperinvasive and apathogenic lineages did not reveal unambiguous hints towards indispensable virulence factors. Here, in a systems biological approach we compared gene expressi...

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Detalles Bibliográficos
Autores principales: Ampattu, Biju Joseph, Hagmann, Laura, Liang, Chunguang, Dittrich, Marcus, Schlüter, Andreas, Blom, Jochen, Krol, Elizaveta, Goesmann, Alexander, Becker, Anke, Dandekar, Thomas, Müller, Tobias, Schoen, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383966/
https://www.ncbi.nlm.nih.gov/pubmed/28388876
http://dx.doi.org/10.1186/s12864-017-3616-7