The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region

Ionotropic glutamate receptors (iGluRs) are responsible for most of the fast excitatory communication between neurons in our brain. The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-ser...

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Detalles Bibliográficos
Autores principales: Tapken, Daniel, Steffensen, Thomas Bielefeldt, Leth, Rasmus, Kristensen, Lise Baadsgaard, Gerbola, Alexander, Gajhede, Michael, Jørgensen, Flemming Steen, Olsen, Lars, Kastrup, Jette Sandholm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384001/
https://www.ncbi.nlm.nih.gov/pubmed/28387240
http://dx.doi.org/10.1038/srep46145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384001/
https://www.ncbi.nlm.nih.gov/pubmed/28387240
http://dx.doi.org/10.1038/srep46145

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