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Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer

BACKGROUND: Dendritic cells (DCs) enhance the quality of anti-tumor immune response in patients with cancer. Thus, we posit that DC-based immunotherapy, in conjunction with toll-like receptor (TLR)-3 agonist poly-ICLC, is a promising approach for harnessing immunity against metastatic or locally adv...

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Detalles Bibliográficos
Autores principales: Mehrotra, Shikhar, Britten, Carolyn D., Chin, Steve, Garrett-Mayer, Elizabeth, Cloud, Colleen A., Li, Mingli, Scurti, Gina, Salem, Mohamed L., Nelson, Michelle H., Thomas, Melanie B., Paulos, Chrystal M., Salazar, Andres M., Nishimura, Michael I., Rubinstein, Mark P., Li, Zihai, Cole, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384142/
https://www.ncbi.nlm.nih.gov/pubmed/28388966
http://dx.doi.org/10.1186/s13045-017-0459-2