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Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

BACKGROUND: Birth cohort studies link gestational diabetes mellitus (GDM) with impaired cognitive performance in the offspring. However, the mechanisms involved are unknown. We tested the hypothesis that obesity-associated GDM induces chronic neuroinflammation and disturbs the development of neurona...

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Detalles Bibliográficos
Autores principales: Vuong, Billy, Odero, Gary, Rozbacher, Stephanie, Stevenson, Mackenzie, Kereliuk, Stephanie M., Pereira, Troy J., Dolinsky, Vernon W., Kauppinen, Tiina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384149/
https://www.ncbi.nlm.nih.gov/pubmed/28388927
http://dx.doi.org/10.1186/s12974-017-0859-9