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Expression, Functional Characterization, and Solid-State NMR Investigation of the G Protein-Coupled GHS Receptor in Bilayer Membranes

The expression, functional reconstitution and first NMR characterization of the human growth hormone secretagogue (GHS) receptor reconstituted into either DMPC or POPC membranes is described. The receptor was expressed in E. coli. refolded, and reconstituted into bilayer membranes. The molecule was...

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Detalles Bibliográficos
Autores principales: Schrottke, Stefanie, Kaiser, Anette, Vortmeier, Gerrit, Els-Heindl, Sylvia, Worm, Dennis, Bosse, Mathias, Schmidt, Peter, Scheidt, Holger A., Beck-Sickinger, Annette G., Huster, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384189/
https://www.ncbi.nlm.nih.gov/pubmed/28387359
http://dx.doi.org/10.1038/srep46128