Characterization of O-acetylation in sialoglycans by MALDI-MS using a combination of methylamidation and permethylation

O-Acetylation of sialic acid in protein N-glycans is an important modification and can occur at either 4-, 7-, 8- or 9-position in various combinations. This modification is usually labile under alkaline reaction conditions. Consequently, a permethylation-based analytical method, which has been wide...

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Detalles Bibliográficos
Autores principales: Wu, Zhaoguan, Li, Henghui, Zhang, Qiwei, Liu, Xin, Zheng, Qi, Li, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384204/
https://www.ncbi.nlm.nih.gov/pubmed/28387371
http://dx.doi.org/10.1038/srep46206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384204/
https://www.ncbi.nlm.nih.gov/pubmed/28387371
http://dx.doi.org/10.1038/srep46206

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