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Characterization of O-acetylation in sialoglycans by MALDI-MS using a combination of methylamidation and permethylation
O-Acetylation of sialic acid in protein N-glycans is an important modification and can occur at either 4-, 7-, 8- or 9-position in various combinations. This modification is usually labile under alkaline reaction conditions. Consequently, a permethylation-based analytical method, which has been wide...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384204/ https://www.ncbi.nlm.nih.gov/pubmed/28387371 http://dx.doi.org/10.1038/srep46206 |