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An analytic approximation of the feasible space of metabolic networks

Assuming a steady-state condition within a cell, metabolic fluxes satisfy an underdetermined linear system of stoichiometric equations. Characterizing the space of fluxes that satisfy such equations along with given bounds (and possibly additional relevant constraints) is considered of utmost import...

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Detalles Bibliográficos
Autores principales: Braunstein, Alfredo, Muntoni, Anna Paola, Pagnani, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384209/
https://www.ncbi.nlm.nih.gov/pubmed/28382977
http://dx.doi.org/10.1038/ncomms14915