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Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids
α-amino acids bearing aromatic side chains are important synthetic units in the synthesis of peptides and natural products. Although various β-C-H arylation methodologies for amino acid derivatives involving the assistance of directing groups have been extensively developed, syntheses that directly...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384235/ https://www.ncbi.nlm.nih.gov/pubmed/28383026 http://dx.doi.org/10.1038/ncomms14904 |