Serum pharmacokinetics and coagulation aberration induced by sodium dehydroacetate in male and female Wistar rats

Sodium dehydroacetate (Na-DHA) is used as a preservative in food, animal feeds and cosmetics. Severe haemorrhage in organs and prolongation of coagulation factors in Sprague–Dawley rats has been reported upon oral administration of Na-DHA. We investigated alterations in coagulation parameters and se...

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Detalles Bibliográficos
Autores principales: Zhang, Yumei, Ying, Donglai, Liu, Hao, Yu, Zengrong, Han, Lingling, Xie, Jiayu, Xie, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384240/
https://www.ncbi.nlm.nih.gov/pubmed/28387309
http://dx.doi.org/10.1038/srep46210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384240/
https://www.ncbi.nlm.nih.gov/pubmed/28387309
http://dx.doi.org/10.1038/srep46210

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