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Serum pharmacokinetics and coagulation aberration induced by sodium dehydroacetate in male and female Wistar rats
Sodium dehydroacetate (Na-DHA) is used as a preservative in food, animal feeds and cosmetics. Severe haemorrhage in organs and prolongation of coagulation factors in Sprague–Dawley rats has been reported upon oral administration of Na-DHA. We investigated alterations in coagulation parameters and se...
Autores principales: | Zhang, Yumei, Ying, Donglai, Liu, Hao, Yu, Zengrong, Han, Lingling, Xie, Jiayu, Xie, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384240/ https://www.ncbi.nlm.nih.gov/pubmed/28387309 http://dx.doi.org/10.1038/srep46210 |
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