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Discovery of new muscarinic acetylcholine receptor antagonists from Scopolia tangutica

Scopolia tangutica (S. tangutica) is a traditional Chinese medicinal plant used for antispasmodics, anesthesia, analgesia and sedation. Its pharmacological activities are mostly associated with the antagonistic activity at muscarinic acetylcholine receptors (mAchRs) of several known alkaloids such a...

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Detalles Bibliográficos
Autores principales: Du, Nana, Liu, Yanfang, Zhang, Xiuli, Wang, Jixia, Zhao, Jianqiang, He, Jian, Zhou, Han, Mei, Lijuan, Liang, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384254/
https://www.ncbi.nlm.nih.gov/pubmed/28387362
http://dx.doi.org/10.1038/srep46067