Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients

The changes of the upper airway after large retraction of the incisors in adult class I bimaxillary protrusion patients were assessed mainly focused on the anatomic variation and ignored the functional changes. This study aimed to investigate the changes of the upper airway in adult class I bimaxill...

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Autores principales: Zheng, Zhe, Liu, Hong, Xu, Qi, Wu, Wei, Du, Liling, Chen, Hong, Zhang, Yiwen, Liu, Dongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384277/
https://www.ncbi.nlm.nih.gov/pubmed/28387372
http://dx.doi.org/10.1038/srep45706
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author Zheng, Zhe
Liu, Hong
Xu, Qi
Wu, Wei
Du, Liling
Chen, Hong
Zhang, Yiwen
Liu, Dongxu
author_facet Zheng, Zhe
Liu, Hong
Xu, Qi
Wu, Wei
Du, Liling
Chen, Hong
Zhang, Yiwen
Liu, Dongxu
author_sort Zheng, Zhe
collection PubMed
description The changes of the upper airway after large retraction of the incisors in adult class I bimaxillary protrusion patients were assessed mainly focused on the anatomic variation and ignored the functional changes. This study aimed to investigate the changes of the upper airway in adult class I bimaxillary protrusion patients after extraction treatment using the functional images based on computational fluid dynamics (CFD). CFD was implemented after 3D reconstruction based on the CBCT of 30 patients who have completed extraction treatment. After treatment, pressure drop in the minimum area, oropharynx, and hypopharynx increased significantly. The minimum pressure and the maximum velocity mainly located in the hypopharynx in pre-treatment while they mostly occured in the oropharynx after treatment. Statistically significant correlation between pressure drop and anatomic parameters, pressure drop and treatment outcomes was found. No statistical significance changes in pressure drop and volume of nasopharynx was found. This study suggested that the risk of pharyngeal collapsing become higher after extraction treatment with maximum anchorage in bimaxillary protrusion adult patients. Those adverse changes should be taken into consideration especially for high-risk patients to avoid undesired weakening of the respiratory function in clinical treatment.
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spelling pubmed-53842772017-04-11 Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients Zheng, Zhe Liu, Hong Xu, Qi Wu, Wei Du, Liling Chen, Hong Zhang, Yiwen Liu, Dongxu Sci Rep Article The changes of the upper airway after large retraction of the incisors in adult class I bimaxillary protrusion patients were assessed mainly focused on the anatomic variation and ignored the functional changes. This study aimed to investigate the changes of the upper airway in adult class I bimaxillary protrusion patients after extraction treatment using the functional images based on computational fluid dynamics (CFD). CFD was implemented after 3D reconstruction based on the CBCT of 30 patients who have completed extraction treatment. After treatment, pressure drop in the minimum area, oropharynx, and hypopharynx increased significantly. The minimum pressure and the maximum velocity mainly located in the hypopharynx in pre-treatment while they mostly occured in the oropharynx after treatment. Statistically significant correlation between pressure drop and anatomic parameters, pressure drop and treatment outcomes was found. No statistical significance changes in pressure drop and volume of nasopharynx was found. This study suggested that the risk of pharyngeal collapsing become higher after extraction treatment with maximum anchorage in bimaxillary protrusion adult patients. Those adverse changes should be taken into consideration especially for high-risk patients to avoid undesired weakening of the respiratory function in clinical treatment. Nature Publishing Group 2017-04-07 /pmc/articles/PMC5384277/ /pubmed/28387372 http://dx.doi.org/10.1038/srep45706 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zheng, Zhe
Liu, Hong
Xu, Qi
Wu, Wei
Du, Liling
Chen, Hong
Zhang, Yiwen
Liu, Dongxu
Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients
title Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients
title_full Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients
title_fullStr Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients
title_full_unstemmed Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients
title_short Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients
title_sort computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class i bimaxillary protrusion patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384277/
https://www.ncbi.nlm.nih.gov/pubmed/28387372
http://dx.doi.org/10.1038/srep45706
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