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Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome

Down syndrome (DS), present in nearly six million people, is associated with an extremely high risk to develop Alzheimer's disease (AD). Amyloid-β and tau pathology are omnipresent from age 40 years onward, but clinical symptoms do not appear in all DS individuals. Dementia diagnostics is compl...

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Detalles Bibliográficos
Autores principales: Dekker, Alain D., Fortea, Juan, Blesa, Rafael, De Deyn, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384293/
https://www.ncbi.nlm.nih.gov/pubmed/28413821
http://dx.doi.org/10.1016/j.dadm.2017.02.006