Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis

The platelet-derived growth factor receptor alpha (PDGFRα) exhibits divergent effects in skeletal muscle. At physiological levels, signaling through this receptor promotes muscle development in growing embryos and proper angiogenesis in regenerating adult muscle.(1,2) However, both increased PDGF li...

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Detalles Bibliográficos
Autores principales: Mueller, Alisa A., van Velthoven, Cindy T., Fukumoto, Kathryn D., Cheung, Tom H., Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384334/
https://www.ncbi.nlm.nih.gov/pubmed/27894125
http://dx.doi.org/10.1038/nature20160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384334/
https://www.ncbi.nlm.nih.gov/pubmed/27894125
http://dx.doi.org/10.1038/nature20160

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