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Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas

Indoleamine 2,3-deoxygenase 1 (IDO1) induces immune tolerance in the tumor microenvironment (TME) and is recognized as a potential therapeutic target. We studied the expression of both IDO1 and the related tryptophan 2,3-dioxygenase (TDO) in several different subtypes of cutaneous T-cell lymphoma (C...

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Detalles Bibliográficos
Autores principales: Maliniemi, Pilvi, Laukkanen, Kirsi, Väkevä, Liisa, Dettmer, Katja, Lipsanen, Tuomas, Jeskanen, Leila, Bessede, Alban, Oefner, Peter J., Kadin, Marshall E., Ranki, Annamari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384345/
https://www.ncbi.nlm.nih.gov/pubmed/28405495
http://dx.doi.org/10.1080/2162402X.2016.1273310