Activation of LINE-1 Retrotransposon Increases the Risk of Epithelial-Mesenchymal Transition and Metastasis in Epithelial Cancer

Epithelial cancers comprise 80-90% of human cancers. During the process of cancer progression, cells lose their epithelial characteristics and acquire stem-like mesenchymal features that are resistant to chemotherapy. This process, termed the epithelial-mesenchymal transition (EMT), plays a critical...

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Detalles Bibliográficos
Autores principales: Rangasamy, D., Lenka, N., Ohms, S., Dahlstrom, J.E., Blackburn, A.C., Board, P.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384359/
https://www.ncbi.nlm.nih.gov/pubmed/26321759
http://dx.doi.org/10.2174/1566524015666150831130827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384359/
https://www.ncbi.nlm.nih.gov/pubmed/26321759
http://dx.doi.org/10.2174/1566524015666150831130827

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