BMP6 Regulates Proliferation and Apoptosis of Human Sertoli Cells Via Smad2/3 and Cyclin D1 Pathway and DACH1 and TFAP2A Activation

Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms underlying human Sertoli cell development remain largely elusive. Here we examined the function and signaling pathways of BMP6 in regulating human Sertoli cells. RT-PCR, immunocytochemistry and Western blots r...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Yuan, Qingqing, Sun, Min, Niu, Minghui, Wen, Liping, Fu, Hongyong, Zhou, Fan, Chen, Zheng, Yao, Chencheng, Hou, Jingmei, Shen, Ruinan, Lin, Qisheng, Liu, Wenjie, Jia, Ruobing, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384448/
https://www.ncbi.nlm.nih.gov/pubmed/28387750
http://dx.doi.org/10.1038/srep45298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384448/
https://www.ncbi.nlm.nih.gov/pubmed/28387750
http://dx.doi.org/10.1038/srep45298

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