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Improving ancient DNA genome assembly

Most reconstruction methods for genomes of ancient origin that are used today require a closely related reference. In order to identify genomic rearrangements or the deletion of whole genes, de novo assembly has to be used. However, because of inherent problems with ancient DNA, its de novo assembly...

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Detalles Bibliográficos
Autores principales: Seitz, Alexander, Nieselt, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384568/
https://www.ncbi.nlm.nih.gov/pubmed/28392981
http://dx.doi.org/10.7717/peerj.3126