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Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis

The tumor microenvironment is critical for metastasis to occur. Subcutaneous xenografts of tumors in immunodeficient mice are usually encapsulated and rarely metastasize as opposed to orthotopic tumors which metastasize if the original tumor was metastatic. In the present report, we were able to rec...

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Detalles Bibliográficos
Autores principales: Murata, Takuya, Mekada, Eisuke, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384587/
https://www.ncbi.nlm.nih.gov/pubmed/28103135
http://dx.doi.org/10.1080/15384101.2017.1281486