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Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis
The tumor microenvironment is critical for metastasis to occur. Subcutaneous xenografts of tumors in immunodeficient mice are usually encapsulated and rarely metastasize as opposed to orthotopic tumors which metastasize if the original tumor was metastatic. In the present report, we were able to rec...
Autores principales: | Murata, Takuya, Mekada, Eisuke, Hoffman, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384587/ https://www.ncbi.nlm.nih.gov/pubmed/28103135 http://dx.doi.org/10.1080/15384101.2017.1281486 |
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