A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

Although several in vitro and ex vivo evidence support the existence of lactate exchange between astrocytes and neurons, a direct demonstration in vivo is still lacking. In the present study, a lentiviral vector carrying a short hairpin RNA (shRNA) was used to downregulate the expression of the mono...

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Detalles Bibliográficos
Autores principales: Mazuel, Leslie, Blanc, Jordy, Repond, Cendrine, Bouchaud, Véronique, Raffard, Gérard, Déglon, Nicole, Bonvento, Gilles, Pellerin, Luc, Bouzier-Sore, Anne-Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384673/
https://www.ncbi.nlm.nih.gov/pubmed/28388627
http://dx.doi.org/10.1371/journal.pone.0174990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384673/
https://www.ncbi.nlm.nih.gov/pubmed/28388627
http://dx.doi.org/10.1371/journal.pone.0174990

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