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Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer
PURPOSE: A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicability of a microdose DDI study. PATIENTS AND METHODS: Six hea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384691/ https://www.ncbi.nlm.nih.gov/pubmed/28408803 http://dx.doi.org/10.2147/DDDT.S131797 |